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1) Atypical Antipsychotic are all except______________? a. Olanzepine b. Clozapine c. Risperidone d. Thioridazone
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2) Benzodiazepine antagonist is________________? a. Flumazenil b. Furazolidone c. Naloxone d. Naltrexone
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3) Which one of the following is NOT an ergot alkaloids_____________? a. Bromocriptine b. Lysergic acid diethylamide (LSD) c. Ketanserin d. Methysergide
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4) BEnzodiazepines are true in___________________? a. Produce distortion in sleep more than other sedatives b. More safe than other sedatives when take in larger amounts c. After metabolism of other drugs in liver d. All have metabolically active substrates
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5) Which of the following is true about parasympathetic nervous system ? a. Ach is transmitter at both pre & post synaptic junction b. It causes dilatation of skeletal muscles c. Post ganglionic fibres are longer than pre ganglionic fibres d. Noradrenalin is the neurotransmitter at post ganglionic junction
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6) Drugs like barbiturates precipitate symptoms of prophyria because______________? a. They depress ALA synthase b. They inhibit ALA synthase c. They induce heme oxygenase d. They inhibit heme oxygenase
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7) The statement Not true of Selective Cox – 2 inhibitor is________________? a. The analgesic and anti-inflammatory effects identical to that of Non-selective NSAID b. They do not offer the cardio protective effect c. Safe in patients with renal insufficiency d. Fewer incidence of gastrointestinal side effect
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8) Which one of the following muscle relaxant has the maximum duration of action ? a. Atracurium b. Vecuronium c. Rocuronium d. Doxacurium
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9) All are symptoms of opiate withdrawls except______________? a. Diarrhea b. Lacrimation c. Mydriasis d. Excessive speech
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10) Buprenorphine acts by following mechanism________________? a. Mu receptor antagonist b. Kappa receptor antagonist c. Mu receptor partial agnoist d. Kappa receptor partial agonist
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11) A patient with grandmal epilepsy would likely be under treatment with_______________? a. Meprobamate b. Pentobarbital c. Trimethadione d. Phenytoin
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12) Respiratory depression is seen with_____________? a. Tranquilizers b. Non-barbiturates c. Synthetic narcotics d. Antidepressants
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13) The first choice of drug for patitmal seizure is________________? a. Phentoin sodium b. Carbamazepine c. Phenobarbitone d. None of the above
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14) An untoward effect of that is common to all phenothiazines is______________? a. A marked increase in blood pressure b. Rigidity and tremor at rest, particularly with prolonged use c. Suppression of prolacin d. Nausea
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15) Platelet aggregation in inhibited by all except_______________? a. Indomenthacin b. Salicylates c. Dypyradimole d. Phenobarbitone
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16) Salicylate administration is contraindicated in pregnancy because_______________? a. It delay onset of labour b. Causes pulmonary hypertension of newborn c. Readily croses placental barrier d. All of these
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17) Which of the following is a non steroidal anti inflammatory agent with a tendency to produce blood dyscrasias ? a. Ibuprofen b. Indomethacin c. Aspirin d. B & C
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18) The principle central action of caffeine is on the________________? a. Cerebral cortex b. Corpus callosum c. Hypothalamus d. Spinal cord
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19) An antiepileptic drug used in petitmal epilepsy is______________? a. Phenobarbitonse b. Dilantoin sodium c. Diazepam d. Ethosuximide
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20) NSAID which undergoes enterohepatic circulation______________? a. Phenylbutazone b. Piroxicam c. Aspirin d. Ibuprofen
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21) Acute Barbiturate poisoning results in_______________? a. Renal failure b. Liver failure c. Respiratory failure d. Convulsions
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22) One of the obious consequences of alchol ( ethenol), ingestion in many individual is facial flushing and increased heart rate triggered off by alcohol getting metabolized to______________? a. Formaldehyde b. Acetaldehyde c. Propanaldehyde d. Butanaldehyde
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23) A 50 year old female with end stage renal disease (ESRD) develops pulmonary tuberculosis. Which one of the following drugs should be used in a reduced dose ? a. Rifampicin b. Isoniazide c. Pyrazamide d. Ethambutol
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24) Carbamazepine is a type of___________? a. Antidepressant b. Antinflammatory c. Antibiotic d. Antiemetic
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25) Morphine a powerful opioid analgesic drug should be avoided in all the following conditions except____________? a. Left ventricular failure b. Bronchial asthma c. Constipation d. A & C
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26) An attack of migraine can be easily terminated by___________? a. Acetylcholine b. Ergotamine c. Morphine d. Ibuprofen
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27) One of the benzodiazepines (BDZ) comparatively safe in pregnancy is (Category-B) ? a. Alprozolam b. Zolpidem c. Lorazepam d. None of the above
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28) Drug which causes gingival hyperplasia_____________? a. Nifedipine b. Erythromycin c. Cyclosporin d. Aspirin e. Both A & C
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29) The intramuscular administration of 0.6 mg of atropine sulphate to a 50 kg adult may produce all of the following effects except________________? a. Bradycardia b. Decreased salivation c. Decreased sweating d. Mydriasis
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30) IV ultrashort acting barbiturate_____________? a. Meprobamate b. Pentobarbitone c. Thiopentone d. Phenobarbitone
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