Pharmacology Mcqs - Set 16

1)   The aminoglycoside with least toxic effect is_____________?

a. Ethambutol
b. Isoniazid
c. Streptomycin
d. Kanamycin
Answer  Explanation 

ANSWER: Streptomycin

Explanation:
No explanation is available for this question!


2)   Drug which is most unsafe during pregnancy is____________?

a. Ethambutol
b. Streptomycin
c. Kanamycin
d. B & C
Answer  Explanation 

ANSWER: B & C

Explanation:
No explanation is available for this question!


3)   Tetracycline in children causes____________?

a. Calcification
b. Missing teeth
c. Discolored teeth
d. Peg teeth
Answer  Explanation 

ANSWER: Discolored teeth

Explanation:
No explanation is available for this question!


4)   Tetracycline is more preferred in periodontics because______________?

a. It is broad spectrum antibiotic
b. It has anticollagenolytic effect
c. All of the above
d. None of the above
Answer  Explanation 

ANSWER: All of the above

Explanation:
No explanation is available for this question!


5)   The most serious side effect of drug chloramp henicol is______________?

a. Candidiasis
b. Photosensitivity
c. Bone marrow depression
d. Angioneurotic oedema
Answer  Explanation 

ANSWER: Bone marrow depression

Explanation:
No explanation is available for this question!


6)   Which of the following drug control lepramin reaction____________?

a. Dapsone
b. Streptomycin
c. Clofazimine
d. Ethambutol
Answer  Explanation 

ANSWER: Clofazimine

Explanation:
No explanation is available for this question!


7)   Oral contraceptive failure occurs in a patient on Rifampicin because of____________?

a. Rifampicin induce the metabolism of contra ceptive
b. Rifampicin simulates gonadotropin relase from pituitary
c. Rifampicin decrease the secretion of progestin
d. Rifampicin antagonize the action of oral contraceptive
Answer  Explanation 

ANSWER: Rifampicin induce the metabolism of contra ceptive

Explanation:
No explanation is available for this question!


8)   Optic neuritis is a side effect of______________?

a. Rifampicin
b. INH
c. Pyrazinamide
d. Ethambutol
Answer  Explanation 

ANSWER: Ethambutol

Explanation:
No explanation is available for this question!


9)   Among the drugs given below, which is LEAST likely to be implicated in drug induced hepatitis ?

a. Isoniazid
b. Streptomycin
c. Ripampicin
d. Pyrazinamide
Answer  Explanation 

ANSWER: Streptomycin

Explanation:
No explanation is available for this question!


10)   Which of the following is caused by Amphotericin B____________?

a. Hypo Kalemia
b. Hyperkalemia
c. Hypermagnesemia
d. Hyponatremia
Answer  Explanation 

ANSWER: Hypo Kalemia

Explanation:
No explanation is available for this question!


11)   Oral infection by penicillinase producing organisms should be treated with____________?

a. Ampicillin
b. Dicloxacillin
c. Erythromycin
d. Any of the above
Answer  Explanation 

ANSWER: Dicloxacillin

Explanation:
No explanation is available for this question!


12)   Stepwise mutation for drug resistance is seen with_____________?

a. Penicillin
b. Streptomycin
c. Garamycin
d. Kanamycin
Answer  Explanation 

ANSWER: Penicillin

Explanation:
No explanation is available for this question!


13)   Which of the following penicillins is given by oral route ?

a. Benzyl penicillin
b. Benzathine penicillin
c. Procaine pencillin
d. Penicillin V / Phenoxymethyl penicillin
Answer  Explanation 

ANSWER: Penicillin V / Phenoxymethyl penicillin

Explanation:
No explanation is available for this question!


14)   Ototoxicity and nephrotoxicity is caused by______________?

a. Antiemetic
b. Antiviral
c. Antifungal
d. antibiotic
Answer  Explanation 

ANSWER: antibiotic

Explanation:
No explanation is available for this question!


15)   One of the below mentioned penicillin is NOT given orally______________?

a. Amoxicillin
b. Carbenicillin
c. Cloxacillin
d. Phenoxymethy penicillin
Answer  Explanation 

ANSWER: Carbenicillin

Explanation:
No explanation is available for this question!


16)   Combination chemotherapy is used in tuberculosis in order to reduce____________?

a. Side effects of drugs
b. Cost of therapy
c. Dosage of drugs
d. Development of drug resistance
Answer  Explanation 

ANSWER: Development of drug resistance

Explanation:
No explanation is available for this question!


17)   Which one of the following antibiotics chelates with calcium ?

a. pencillin
b. Tetracycline
c. Cephalosporins
d. Erythromycin
Answer  Explanation 

ANSWER: Tetracycline

Explanation:
No explanation is available for this question!


18)   Clavulanic acid added to ampicillin causes_____________?

a. Increase effectivity against gram-negative organisms
b. Inhibition of B-lactamases
c. Increase the effectiveness against delta lactamase producing organism
d. Increase effectivity against gram-positive organisms
Answer  Explanation 

ANSWER: Inhibition of B-lactamases

Explanation:
No explanation is available for this question!


19)   Cephalosporines have all of the following interactions except_____________?

a. Show cross sensitivity with penicillins
b. Are penicillinase resistant
c. Have a broad spectrum but are inactive against anaerobes
d. Are used in upper respiratory tract infections
Answer  Explanation 

ANSWER: Are penicillinase resistant

Explanation:
No explanation is available for this question!


20)   In the treatment of intestinal of intestinal and extraintestinal amoebiasis which of the following drug is useful____________?

a. Diloxane
b. Metronidazole
c. Chloroquine
d. Cefaclor
Answer  Explanation 

ANSWER: Metronidazole

Explanation:
No explanation is available for this question!


21)   The drug which gives orange colour to the urine is______________?

a. Rifampicin
b. Ethambutol
c. INH
d. Streptomycin
Answer  Explanation 

ANSWER: Rifampicin

Explanation:
No explanation is available for this question!


22)   Which on of the following is penicillinase resistant penicillin_______________?

a. Amoxycillin
b. Cloxacillin
c. Ampicillin
d. Penicillin G
Answer  Explanation 

ANSWER: Cloxacillin

Explanation:
No explanation is available for this question!


23)   Desfuroxamide is a drug used for____________?

a. Kala azar
b. Pernicious anaemia
c. Pain control
d. Thalassemia
Answer  Explanation 

ANSWER: Thalassemia

Explanation:
No explanation is available for this question!


24)   A patient has seasonal allergic rhinitis and is on terfenadine, He develps cardiac arrhythmias after a course of antibiotics. Which of the following antibiotic could have been given_____________?

a. Ampicillin
b. Tetracyclin
c. Erythromycin
d. Co-trimoxazole
Answer  Explanation 

ANSWER: Erythromycin

Explanation:
No explanation is available for this question!


25)   Antifungal drug not used in the treatment of imtestinal candidiasis______________?

a. Amphotericin
b. Nystatin
c. Ketoconazole
d. Clotrimazole
Answer  Explanation 

ANSWER: Clotrimazole

Explanation:
No explanation is available for this question!


26)   The drug of choice for treatment of tyhoid is____________?

a. Tetracycline
b. Metronidazole
c. Ciprofloxacin
d. Cefotaxim
Answer  Explanation 

ANSWER: Ciprofloxacin

Explanation:
No explanation is available for this question!


27)   The bacterial resistance to tetracycline is due to___________?

a. Alteration of drug binding sites
b. Alteration of dehydrofolate reductase
c. Inactivation of drug by enzymes
d. Decreased uptake of drug by bacteria
Answer  Explanation 

ANSWER: Inactivation of drug by enzymes

Explanation:
No explanation is available for this question!


28)   Mechanism of action of quinolones is______________?

a. Inhibits DNA gyrase
b. Inhibits Bacterial protein synthesis
c. Inhibits bacterial cell wall synthesis
d. Inhibits intake of folic acid
Answer  Explanation 

ANSWER: Inhibits DNA gyrase

Explanation:
No explanation is available for this question!


29)   Tetracycline is contraindicated in_____________?

a. Children
b. Pregnancy
c. Renal failure
d. All of the above
Answer  Explanation 

ANSWER: All of the above

Explanation:
No explanation is available for this question!


30)   The antibiotic of choice in patients sensitive to penicillin is___________?

a. Erythromycin
b. Streptomycin
c. Tetracycline
d. Chloramphenicol
Answer  Explanation 

ANSWER: Erythromycin

Explanation:
No explanation is available for this question!