1) The aminoglycoside with least toxic effect is_____________? a. Ethambutol b. Isoniazid c. Streptomycin d. Kanamycin
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2) Drug which is most unsafe during pregnancy is____________? a. Ethambutol b. Streptomycin c. Kanamycin d. B & C
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3) Tetracycline in children causes____________? a. Calcification b. Missing teeth c. Discolored teeth d. Peg teeth
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4) Tetracycline is more preferred in periodontics because______________? a. It is broad spectrum antibiotic b. It has anticollagenolytic effect c. All of the above d. None of the above
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5) The most serious side effect of drug chloramp henicol is______________? a. Candidiasis b. Photosensitivity c. Bone marrow depression d. Angioneurotic oedema
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6) Which of the following drug control lepramin reaction____________? a. Dapsone b. Streptomycin c. Clofazimine d. Ethambutol
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7) Oral contraceptive failure occurs in a patient on Rifampicin because of____________? a. Rifampicin induce the metabolism of contra ceptive b. Rifampicin simulates gonadotropin relase from pituitary c. Rifampicin decrease the secretion of progestin d. Rifampicin antagonize the action of oral contraceptive
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8) Optic neuritis is a side effect of______________? a. Rifampicin b. INH c. Pyrazinamide d. Ethambutol
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9) Among the drugs given below, which is LEAST likely to be implicated in drug induced hepatitis ? a. Isoniazid b. Streptomycin c. Ripampicin d. Pyrazinamide
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10) Which of the following is caused by Amphotericin B____________? a. Hypo Kalemia b. Hyperkalemia c. Hypermagnesemia d. Hyponatremia
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11) Oral infection by penicillinase producing organisms should be treated with____________? a. Ampicillin b. Dicloxacillin c. Erythromycin d. Any of the above
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12) Stepwise mutation for drug resistance is seen with_____________? a. Penicillin b. Streptomycin c. Garamycin d. Kanamycin
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13) Which of the following penicillins is given by oral route ? a. Benzyl penicillin b. Benzathine penicillin c. Procaine pencillin d. Penicillin V / Phenoxymethyl penicillin
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14) Ototoxicity and nephrotoxicity is caused by______________? a. Antiemetic b. Antiviral c. Antifungal d. antibiotic
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15) One of the below mentioned penicillin is NOT given orally______________? a. Amoxicillin b. Carbenicillin c. Cloxacillin d. Phenoxymethy penicillin
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16) Combination chemotherapy is used in tuberculosis in order to reduce____________? a. Side effects of drugs b. Cost of therapy c. Dosage of drugs d. Development of drug resistance
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17) Which one of the following antibiotics chelates with calcium ? a. pencillin b. Tetracycline c. Cephalosporins d. Erythromycin
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18) Clavulanic acid added to ampicillin causes_____________? a. Increase effectivity against gram-negative organisms b. Inhibition of B-lactamases c. Increase the effectiveness against delta lactamase producing organism d. Increase effectivity against gram-positive organisms
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19) Cephalosporines have all of the following interactions except_____________? a. Show cross sensitivity with penicillins b. Are penicillinase resistant c. Have a broad spectrum but are inactive against anaerobes d. Are used in upper respiratory tract infections
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20) In the treatment of intestinal of intestinal and extraintestinal amoebiasis which of the following drug is useful____________? a. Diloxane b. Metronidazole c. Chloroquine d. Cefaclor
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21) The drug which gives orange colour to the urine is______________? a. Rifampicin b. Ethambutol c. INH d. Streptomycin
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22) Which on of the following is penicillinase resistant penicillin_______________? a. Amoxycillin b. Cloxacillin c. Ampicillin d. Penicillin G
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23) Desfuroxamide is a drug used for____________? a. Kala azar b. Pernicious anaemia c. Pain control d. Thalassemia
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24) A patient has seasonal allergic rhinitis and is on terfenadine, He develps cardiac arrhythmias after a course of antibiotics. Which of the following antibiotic could have been given_____________? a. Ampicillin b. Tetracyclin c. Erythromycin d. Co-trimoxazole
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25) Antifungal drug not used in the treatment of imtestinal candidiasis______________? a. Amphotericin b. Nystatin c. Ketoconazole d. Clotrimazole
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26) The drug of choice for treatment of tyhoid is____________? a. Tetracycline b. Metronidazole c. Ciprofloxacin d. Cefotaxim
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27) The bacterial resistance to tetracycline is due to___________? a. Alteration of drug binding sites b. Alteration of dehydrofolate reductase c. Inactivation of drug by enzymes d. Decreased uptake of drug by bacteria
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28) Mechanism of action of quinolones is______________? a. Inhibits DNA gyrase b. Inhibits Bacterial protein synthesis c. Inhibits bacterial cell wall synthesis d. Inhibits intake of folic acid
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29) Tetracycline is contraindicated in_____________? a. Children b. Pregnancy c. Renal failure d. All of the above
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30) The antibiotic of choice in patients sensitive to penicillin is___________? a. Erythromycin b. Streptomycin c. Tetracycline d. Chloramphenicol
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