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1) The drug for choice for treatment of infection involving non-penicillinase producing staphylococcus is___________? a. Ampicillin b. Erythromycin c. Penicilling G d. Methicillin sodium
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2) The oropharyngeal and oesophageal candidiasis following long-term therapy with a broad spectrum antibiotic can be best treated with____________? a. Griseofulvin b. Amphotericin c. Fluconazole d. Sulfonates
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3) Antibiotic that interferes with DNA function is_____________? a. Metronidazole b. Nystatin c. Tetracycline d. Sulphonamides
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4) Which antibiotic is effective against pseudomonas and indole +ve proteus ? a. Methicillin b. Carbenicillin c. Lincomycin d. Oxacillin
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5) A distinict advantage that tetracyclines have over penicillins is that tetracyclines_____________? a. Have no side effects b. Do not cause superinfections c. Are safer to use during pregnancy d. Have a wider range of antibacterial activity
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6) Which of the following antibiotics is most frequently associated with pseudomembranous colitis ? a. Ampicillin b. Penicillin c. Clindamycin d. Cephalosporin
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7) Prolonged administration of streptomycin may result in damage to the____________? a. Optic nerve b. Facial nerve c. Auditory nerve d. Trigeminal nerve
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8) A patient taking which of the following drug should not eat cheese, etc_____________? a. Tetracycline b. Amoxycillin c. Doxycycline d. Triamterene
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9) The mechanism of action of chloramphenicol is inhibition of synthesis of_____________? a. Cell wall b. Cell membrane c. Protein d. DNA
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10) Granesetron, the antiemetic properties because of____________? a. Dopaminergic receptor – blocking actions b. Gabamimetic actions c. Gaba-inhibitory actions d. Serotonin receptor – blocking action
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11) When broad spectrum antibiotics are administered with coumarin anticoagulants, the anticoagulant action may be____________? a. Reduced because of enhanced hepatic drug metabolism b. Reduced because of increased protein binding c. Increased because of reduction of vitamin sources d. Increase because of decrease renal excretion of the anticoagulant
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12) Peripheral neuritis is a complication of_______________? a. Isoniazid b. Ethambutol c. Rifampicin d. Pirazinamide
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13) A patient suffering from syphilis is given pencillin He may develop_____________? a. Cholestatic Jaundice b. Grey Syndrome c. Fanconi Syndrome d. Jarish – Herxheimer reaction
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14) A child with permanently stained teeth reports, He was most probably administered_____________? a. Disphenyl hydantoin b. Diphenhydramine c. Digoxin d. Doxycycline
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15) Fluconazole is used for the treatment of______________? a. Pemphigus b. Herpes simplex c. Candidiasis d. Syphilis
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16) Which of the following penicillins can be given by IV route ? a. Benzathine b. Procaine c. Crystalline d. Benzathamine
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17) Which drug causes photosensitivity______________? a. Tetracycline b. Aminoglycoside c. Penicillin d. Cephalosporin
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18) Concurrent administration of tetracyclines is most likely to impair the action of_____________? a. Lincomycin b. Chloramphenicol c. Erythromycin d. Penicillin
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19) Penicillin is effective against_____________? a. Neisseria meningitis b. Neisseria gonorrhoeae c. Treponema Pallidum d. All of the above
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20) Which of the following drugs in likely to damage the eighth cranial nerve when administered for a long period of time ? a. Ethambutol b. Isoniazid c. Rifampicin d. Streptomycin
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21) True about aminoglycoside is all except______________? a. Are bacteriostatic b. Distributed only extracellularly c. Excreted unchanged in urine d. Teratogenic
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22) Which of the following is a first generation oral cephalosporin_____________? a. Cephapirin b. Cefadroxil c. Cefaclor d. Cefixime
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23) Best treatment of candidiasis of_____________? a. Mycostatin b. Amphoterin c. Antibiotics d. None of the above
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24) Cyclosporin is used an______________? a. Anticancer drug b. Antibiotic c. Antiarrythmic d. Immunosuppresant
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25) Which of the following is a 4th generation cephalosporin______________? a. Ceftrioxone b. Cefaclor c. Cefepime d. Cefuroxime
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26) Metronidazole______________? a. Has no side-effects b. Is used in management of ANUG c. Is mainly concentrated in saliva d. Is active against gram-positive aerobes
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27) Cross resistance of isoniazid is seen with_____________? a. Rifampicin b. Ethionamide c. Cycloserine d. Ethambutol
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28) The oral microblal fiora of a patient on prolonged broad spectrume antibiotic therapy is predominantly____________? a. Anaerobic b. Gram positive organism c. Gram negative organisms d. Yeast and fungi
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29) True about amoxycillin in comparison to ampicillin is_______________? a. Higher oral biovailability b. Lower oral biovailability c. Equal oral biovailability d. Can be given Parenterally
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30) An aminoglycoside that is often combined with polymyxin and bacitracin for the treatment of topical infection is____________? a. Gentamycin b. Tetracycline c. Aztreonam d. Neomycin
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