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1) Daily loss of iron per day in a healthy adult male is_______________? a. 0.06 mg b. 0.6 mg c. 60 mg d. 600 mg
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2) Genes for sex determination is_____________? a. Shh b. SRY c. AZF d. HOX
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3) HOX gene is responsible for which malformation_____________? a. Polysyndactyly b. Holoprosencephaly c. Mayer Rokitansky syndrome d. Gorlin syndrome
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4) Fibrin degradation product help in detection of_______________? a. haemophilia b. DIC c. Thrombocytopenic purpura d. Thrombasthenia
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5) Syndrome which is characterized by 2X chromosomes and 1Y chromosome is_____________? a. Kleinfelters syndrome b. Down syndrome c. Turner syndrome d. Marfan syndrome
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6) Most common cause of pulmonary embolism ? a. Thrombophebitis b. Endarteritis c. Atheroscleroses d. Lymphangitis
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7) A infant with cleft lip, palate, polydactly, microcephaly with holoprosencephaly, ectodermal scalp defect is suffering from ? a. Trisomy 21 b. Trisomy 18 c. Trisomy 13 d. Turner syndrome
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8) Following is used to stain fungi______________? a. PAS b. Fontania stain c. Ferrous trichrome d. Pearls prussian blue
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9) Which one of the following does not present antigens ? a. NK cells (Netural killer cells) b. Dendritic cells c. Langerhan’s cells d. Macrophages
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10) Egg shell calcification of Hilar Lymphnode is associated with_____________? a. Silicosis b. Asbestosis c. Byssinosis d. Anthracosis
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11) Phagocytes kill bacteria through which mechanism_____________? a. Membrane attack complex killing b. Oxidative and non-oxidative killing c. Zipper killing d. Chemotaxis
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12) Not sequelae of cellular events in atheroscierotic infarction_____________? a. Neutrophilic infiltration b. Astrocytes c. Ingress of macrophages d. Intense eosinophilia
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13) A patient has increased number of columnar cells in lower esophagus. He has which of the following change_______________? a. Dysplasia b. Anaplasia c. Metaplasia d. Normal histology
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14) A patient with amenorrhea, short stature, less public hair can be in all of the following except___________? a. 47 XXY b. 46 XY c. 45 X d. 46 XXY
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15) Down syndrome is caused by all except___________? a. Trisomy of 21 chromosome b. Mosaicism of 21 chromosome c. Robersonian translocation of 21.21, 21.18 d. Deletion of 21
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16) NK cells are effective against viral infected cells only if the cell with infection___________? a. Exprss MHC class I proteins b. Unable to express MHC class I proteins c. Express MHC class II proteins d. Unable to express MHC class II proteins
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17) Tumour involving epiphysis of long bone is____________? a. Osteogenic sarcoma b. Osteoclastoma c. Ewings sarcoma d. Chondro sarcoma
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18) A haemophilia person has married to a normal woman Then his___________? a. Daughter are carrier b. Sons are infected c. Daughter are infeted d. All are normal
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19) A 13 year old boy presents with a large mixed lytic and blastic mass in the metaphyseal region of the lower end of femur. The most likely diagnosis is___________? a. Ewing’s sarcoma b. Osteosarcoma c. Chondrosarcoma d. Giant cell tumour
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20) Endotoxic shock is propagated____________? a. Endothelial injury b. Peripheral vasodilation c. Increased vascular permeability d. Cytokine action
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