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1) The world german measles is applied for_____________? a. Rubella b. Rubeola c. Herpes simplex d. Herpetic ginglvostomatitis
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2) Hepatitis A virus is best diagnosed by______________? a. IgM antibodies in serum b. Isolation form stool c. Culture from blood d. Isolation from bile
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3) Which of the following is not a pox virus ? a. Cowpox b. Molluscum contagiosum c. Small pox d. chicken pox
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4) Serological study for prevalence of Hepatitis B is best done by______________? a. Surface antigen b. Surface antibody c. Core antigen d. Core antibody
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5) ELISA test when compared to western blot technique is______________? a. Less sensitive less specific b. More sensitive, more specific c. Less sensitive, more specific d. More sensitive, less specific
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6) The virus which causes Aplastic anemia in chronic hemolytic disease is_______________? a. Adeno b. Hepatitis c. EB virus d. Parvo virus
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7) In HIV, gp 120, envelope glycoproteins bind specifically to______________? a. CD8 T-cells b. CD4 T-cells c. B – cells d. NK – cells
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8) The small nonparticulate protein leading to enhanced replication of HBV as well as HIV is______________? a. HBc Ag b. HBs Ag c. Hbe Ag d. HBx Ag
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9) patients with organ transplants are most frequently infected with______________? a. Hepatitis A b. Hepatitis B c. CMV d. EBV
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10) EBV is responsible for all except______________? a. Nasopharyngeal carcinoma b. Burkitt’s lymphoma c. Hepatoma d. Infectious mononucleosis
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11) Most common tumor associated with AIDS is______________? a. Carcinoma b. Kaposi’s sarcoma c. Melanoma d. Ewing’s sarcoma
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12) The overall effect of HIV is to gradually impair the immune system by interference with______________? a. Helper T lymphocytes b. Natural killer cells c. Plasma cells d. Macrophages
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13) Hepatitis C virus belongs to which one of the following virus groups ? a. Picorna viruses b. Herpes viruses c. Hepadana viruses d. Flavi viruses
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14) Hepatitis B infection spreads through all of the following routes except______________? a. Blood transfusion b. Sexual contact c. Faeco oral route d. Perinatal transmission
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15) Viruses can be isolated from clinical samples by cultivation in the following except_______________? a. Tissue culture b. Embryonated eggs c. Animals d. Chemically defined media
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16) During the Window period of patient with AIDS_______________? a. ELISA IS – ve b. Western Blot is – ve c. Both are – ve d. PCR is – ve
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17) Plaque test is used routinely in virology lab’s for________________? a. Identification of viral disease b. To separate specific clone of virus c. To maintain certain viral culture d. To prepare vaccines
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18) All are oncogenic except________________? a. Anopheles b. Aedes c. Culex d. Mansoni
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19) DNA covering material in a virus is called as________________? a. Capsomere b. Capsid c. Nucleocapsid d. Envelope
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20) All are oncogenic except________________? a. EB virus b. Papilloma virus c. Herpes simplex virus d. Varicella zoster virus
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21) True about HIV are all except______________? a. DNA virus b. Attacks CD4 cells c. Macrophages are the reservoir d. Decrease CD4 count in late stages
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22) EBV causes all except_________________? a. Carcinoma of nasopharynx b. Papilloma c. Infectious mononucleosis d. Burkitt’s lymphoma
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23) Australian antigen is_______________? a. HB Ag b. HBs AG c. HBV d. None of the above
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24) Which of the following methods is adopted for screening HIV infection ? a. Virus isolation b. Western blot followed by ELISA c. ELISA followed by western blot technique d. Polymers chain reaction
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25) Enterically transmitted NANB hepatitis B_____________? a. Hepatitis C b. Hepatitis D c. Hepatitis E d. Hepatitis F
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26) True about immune response of hepatitis B is__________________? a. Antibody of HBs Ag is associated with resistance to infection b. Antibody to HBC is not protective c. Highest titres of anti HBC are found in persistent carriers of HBs Ag d. CMI disappears soon after recover
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27) The best way of detecting the presence of viruses in the infected cell – culture is____________? a. Cytopathic changes in culture cells b. Presence of viral protein in the infected monolayer c. Haemagglutination test d. Haemagglutination inhibition test
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28) The Dane particle is the______________? a. HBV b. IgG anti HAV c. Delta Virus d. HBC Ag
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29) Baby born to mother suffering from AIDS, all are true except________________? a. Failure to thrive b. Have infections c. 50% chances to have AIDS d. All are true
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30) The time gap between appearance of Koplik’s spot and cutaneous rash in measles is________________? a. 24 Hrs b. 3-4 days c. 2 weeks d. 10 days
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