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1) The Process of attenuation can be achieved by all except___________________? a. Growing bacteria in adverse environment b. Growing bacteria in unconventional host c. Serial passage in an experimental host d. Repeated cultures in artificial media
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2) Post streptococcal acute glomerulo nephritis is an example of________________? a. Type I hypersensitivity b. Type II hypersensitivity c. Type III hypersensitivity d. Type IV hypersensitivity
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3) Bacterial cell does not possess___________________? a. dna b. Ribosome c. Mitochondria d. Cell wall
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4) The Manufacturing unit of surgical needle & sutures are sterilized by ________________? a. Gamma-Rays b. X-Rays c. Autoclaving d. Boiling
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5) A child presents with infective skin lesions of the leg. Culture was done which showed gram positive cocci in chains and haemolytic colonies. Which of the following tests will best identify the organism ? a. Bile solubility b. Optochin sensitivity c. Bacitracin sensitivity d. Cataslase positive
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6) Purpose of Sterilization is to eliminate________________? a. Bacteria b. Viruses c. Spore formers d. Fungus
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7) Cell wall deficient bacteria are_______________? a. Escherichia Coli b. Staphylococci c. Spirochetes d. Mycoplasma
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8) The type of immunoglobulin most commonly increased in multiple myeloma is_______________? a. IgG b. IgA c. IgM d. IgD
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9) The function of IgD is______________? a. Antigen recognition by B cells b. Localization protection in external secretion c. Compliment activation d. Reagin activity
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10) Cleavage of IgG molecule by Papin gives rise to:One Fc fragment and two Fab fragments_______________? a. One Fc fragment and two Fab fragments b. One Fc fragment and four Fab fragments c. Two Fc fragments and two Fab fragments d. Two Fc fragment and one Fab fragment
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11) Physical sterilization was discovered by__________________? a. Robert Koch b. Joeph Lister c. John Hunter d. Alexander flemings
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12) The best method of sterilization of dressing powder is_____________? a. Autoclaving b. Hot air oven c. Inspissation d. Tyndallization
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13) One of the following statement about statements about sterilization is not true_______________? a. Liquid paraffin → Dry heat b. Glass syringes → Boiling at 169°C for 60 min c. Flash pasteurization of milk → 72° C for 15 seconds, followed quickly by rapid cooling to 13°C for lower d. Vaccines → Ethylene oxide
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14) Moist heat kills all of the following EXCEPT_______________? a. Brucella b. Mycobacterium c. Salmonella d. Coxiella burnetti
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15) Which component of the cell wall is responsible________________? a. Region I b. Region II c. Region III d. Boivin antigen
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16) T cell matures in______________? a. Payers patch b. Lymph node c. Thymus d. Busra of Fabricius
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17) CD4 cells recognize the antigens in association with_____________? a. MHC I b. MHC II c. MHC III d. B-cell receptor
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18) IL-1 is produced by_________________? a. Helper T cells b. Helper B cells c. Monocytes d. Macrophages
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19) Grave’s disease is an example of type immunologic response_________________? a. Type I b. Type II c. Type III d. Type IV
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20) Type IV hypersensitivity reaction is mediated by which of the following________________? a. B-cells b. Active T cells c. NK cells d. Plasma cells
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21) Which of the following is a live vaccine_____________? a. 17 D b. Salk c. Hepatitis d. HDCV
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22) Techoic acid is present in_____________? a. Cell wall of Gram positive organisms b. Cell wall of Gram negative organisms c. Cytoplasm of Gram positive organisms d. Cytoplasm of Gram negative organisms
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23) Which of the following are correctly matched ? a. Transfer of antibody from mother to child is through colostrum and acquired passive immunity naturally b. Injection of antibodies (Hepatitis) is artificially acquired passive immunity c. Antigenic stimulus given by vaccine (polio) is artificial active immunity d. All of the above
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24) Selective media for MYCOBACTERIUM _____________? a. Sabourauds medium b. Agar – agar c. Lowenstein Jensen medium d. Loefflers serum slope
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25) Which of the following provides best gurantee for sterlization in the heat sterilizer ? a. Using chemical indicator strip or pouch b. Recording a temperature/ pressure readings from sterilizer guage c. Using a bacterial spore test d. Determining the ability of a sterilizer to kill the hepatitis B virus
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26) The serum concentration of which of the following human IgG subclass is maximum ? a. IgG1 b. IgG2 c. IgG3 d. IgG4
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27) Glasswares are sterilised by______________? a. Autoclaving b. Hot air oven c. Incineration d. Formaldehyde
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28) Function of T-lymphocyte is/are________________? a. Production of interferon b. Lymphokine production c. Rosette formation d. All of the above
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29) Haptane is_______________? a. Same as epitopes b. Carrier required for specific antibody production c. High molecular protein d. None of the above
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30) Delayed tuberculin test response is due to_______________? a. B lymphocytes b. T lymphocytes c. Monocytes d. Histiocytes
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