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1) Michaelis-Menten hypothesis states that_____________? a. Rate of enzymatic reaction is independent of substrate concentration b. Rate of non enzymatic reaction is proportional to substrate concentration c. Km is the enzyme substrate complex association constant d. Enzyme- substrate complex formation is essential in enzymatic reaction
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2) Coenzyme responsible for single carbon transfer is______________? a. Acetyl co enzyme A b. Biotin c. THF4 d. Pyridoxine
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3) Hexokinase is a______________? a. Transferase b. Reductase c. Oxidoreductase d. Oxidase
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4) Enzyme + coenzyme constitutes_____________? a. Apoenzyme b. Proenzyme c. Protoenzyme d. Holoenzyme
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5) The amino acid required for the synthesis of haem is______________? a. Glutamine b. Glutamic acid c. Glycine d. Lysine
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6) Ubiqultin is involved in_____________? a. Intracellular proteolysis b. Electron transport chain c. Transport of ATP d. Protein folding
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7) Which of the following is a function of the golgi apparatus ? a. Modification of proteins b. m RNA synthesis c. Protein storage d. t RNA synthesis
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8) The most abundant protein present in body is_____________? a. Globulin b. Albumin c. Collagen d. Hemoglobin
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9) Oligosaccharide is________________? a. Glucose b. Gructose c. Maltose d. Dextrin
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10) Synthesis of protein occurs on_____________? a. Mitochondria b. Poly ribosomes c. Nucleus d. Golgi bodies
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11) Bilirubin is produced from________________? a. Haemoglobin b. Myoglobin c. Gall bladder d. A & B
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12) Bile contains______________? a. Cholic acid b. Chenodeoxycholic acid c. Deoxycholic acid d. Lithocholic acid e. All of the above
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13) Nor epinephrine is converted to epinephrine by______________? a. Dopamine hydroxylase b. Dopa decarboxylase c. O-methylation d. N-methylation
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14) Rate limiting step in adrenaline synthesis is conversion of____________? a. Tyrosine to dopa b. Phenylalanine to tyrosine c. Dopa to dopamine d. Dopamine to nor epinephrine
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15) Which of the following has a ketogenic effect on livers______________? a. Insulin b. Glucagon c. GH d. Androgen
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16) Calcitonin is antagonist_______________? a. Parathyroid hormone b. Thyroxine c. Triidothyronine d. Serotonin
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17) Ribosomes are usually associated with______________? a. Endoplasmic reticulum b. Mitochondria c. Nucleolus d. Plasma membrane
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18) Golgi bodies function are______________? a. Protein lipid synthesis b. Protein synthesis c. Sorting of glycoproteins d. None of the above
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19) Which cell organelle contains DNA_____________? a. Mitochondrion b. Golgi body c. Endoplasmic reticulum d. Centriole
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20) Most importent compansatory mechanism in metabolic acidosis______________? a. Hyperventilation b. Increased NH3 excretion by kidneys c. Increased urinary phosphates d. Increased HCO3 Production
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21) To keep blood PH at 7.4 the HCO3 : H2CO3 ratio should be_____________? a. 20 : 1 b. 30 : 1 c. 15 : 1 d. 1 : 1
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22) Normal blood PH is______________? a. 6.8 – 7.0 b. 7.0 – 7.12 c. 7.38 – 7.4 d. 7.7 – 8.0
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23) Which of the following about biological membrane is true ? a. Lipid moiety is amphipathic b. Rigid assembly of protein, lipid and carbohydrate c. Symmertrical bi leaflet structures d. Lipid and protein moiety are held by covalent interactions
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24) In Cytochrome p450, P stands for____________? a. Structural proteins b. Substrate protiens c. Pigment d. Polymer
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25) Which of the following is false about starvation ketoacidosis ? a. Metabolic acidosis b. Smell of acetone in breath c. Benedict’s test +ve d. Rothera’s test is +ve
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26) A relatively component of the electron transporting respiratory chain is_____________? a. Flavoprotein b. Cytochrome Cl c. Ubiquinone d. Cytochrome A
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27) During phagocytosis the metabolic process called respiratory burst involves activation of_____________? a. Oxidase b. Hydrolase c. Peroxidase d. Dehydrogenase
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28) Which of these organelle functions as the digestive system of the cell ? a. Mitochondria b. Rough endoplasmic reticulum c. Golgi apparatus d. Lysomes
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29) Which one of the following human tissues contains the greatest amount of body glycogen ? a. Liver b. Kidney c. Skeletal muscle d. Cardiac muscle
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30) Which of the following is inclusion of cytoplasm ? a. Endoplasmic reticulum b. Ribosome c. Golgi body d. Glycogen
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