|
1) The first product of glycogenolysis is_____________? a. Glucose 6 phosphatase b. Glucose 1,6 diphosphatase c. Glucose 1- phosphatase d. Fructose 1- phosphatase
|
||||
|
2) Glucose can be synthesized from all except_____________? a. Amino acids b. Glycerol c. Acetoacetate d. Lactic acid
|
||||
|
3) The tissue with the highest glycogen content (mg/100gm)_____________? a. Liver b. Muscle c. Kidneys d. Testes
|
||||
|
4) Major contribution towards gluconeogenesis is by____________? a. Lactate b. Glycerol c. Ketones d. Alanine
|
||||
|
5) An essential for the conversion of glucose to glycogen in liver is____________? a. UTP b. GTP c. Pyruvate Kinase d. Guanosine
|
||||
|
6) Which of the following enzymes use NADP as coenzyme ________________? a. Glyceraldehyde 3 phosphate dehydrogenase b. Lactate dehydrogenase c. Glucose 6-Phosphate dehydrogenase d. Beta hydroxy acyl CoA dehydrogenase
|
||||
|
7) In prolonged starvation the main nergy source of brain is_____________? a. Glucose b. Ketone bodies c. Fructose d. Fatty acids
|
||||
|
8) The citric acid cycle is the final pathway for oxidation of______________? a. Enzymes b. Vitamins c. Minerals d. None of the above
|
||||
|
9) The uptake of glucose by the liver increase following a carbohydrate meal because____________? a. There is increase in phosphorylation of glucose by glucokinase b. GLUT-2 stimulated by insulin c. Glucokinase has a low Km for glucose d. Hexokinase in liver has a high affinity for glucose
|
||||
|
10) Which one of the following enzymes provides a link between glycolysis and the citric acid cycle ? a. Lactate dehydrogenase b. Pyruvate kinase c. Citrate synthase d. Pyruvate dehydrogenase
|
||||
|
11) Increase in pyruvate and lactate is seen in which of the following deficiency ? a. Thiamine b. Pyridoxine c. Niacin d. Vitamin C
|
||||
|
12) Glycogen breakdown leads to formation of______________? a. Glucose b. Lactic acid c. Glucose & Lactic acid d. Glycoprotein
|
||||
|
13) Which is not a oligosaccharide sugar ? a. Galactose b. Lactose c. Maltose d. Sucrose
|
||||
|
14) One molecule of acetyl Co-A gives rise to ________ ATP molecules? a. 2 b. 8 c. 12 d. 32
|
||||
|
15) All these reactions take place inside the mitochondria except____________? a. EMP pathway b. Krebs cylce c. Urea cycle d. Electron transfer
|
||||
|
16) Which of the following is not a product of HMP shunt_____________? a. NADPH b. D fructose 6 phosphate c. D sedoheptulose 5 phosphate d. D glyceraldehyde 3 phosphate
|
||||
|
17) All are true regarding glucose 6 phosphate deficiency except______________? a. Hyperuricemia b. Hyperglycemia c. Defective cori cycle d. Increased mobilization of glycogen from liver
|
||||
|
18) Blood glucose level cannot be augmented by mobilization of muscle glycogen due to lack of_____________? a. G-6-P dehydrogenase b. G-6-P phydrogenase c. Aldolase d. Glucokinase
|
||||
|
19) Galactosemia commonly is due to deficiency of_____________? a. Galactose 1 phosphatase uridyl transferase b. Galactose 1 phosphatase c. Glucose 1 phosphatase d. Glucose 6 phosphatase
|
||||
|
20) In which type of glycogen storage disease is hyper uricemia a feature ? a. I b. II c. III d. IV
|
||||
|
21) McArdles disease is due to the deficiency of_____________? a. Glucose 1 phosphatase b. Glucose 1,6 phosphatase c. Glucose 6 phosphatase d. Myophosphorylase
|
||||
|
22) An enzyme not involved in glycolysis is______________? a. Enolase b. Phosphoglycero mutase c. Aldolase d. Glycerophosphate dehydrogenase
|
||||
|
23) Phosphofructokinase is the key enzyme of______________? a. Glycolysis b. Gluconeogenesis c. Beta oxidation d. TCA cycle
|
||||
|
24) Which metabolite of TCA cycle is used in detoxification of ammonia in brain_____________? a. Alpha ketoglutarate b. Ornithine c. Oxalocetate d. Glycine
|
||||
|
25) In TCA cycle, citrate is converted in to after losing a molecule of H2O_____________? a. Isocitrate b. Cisaconitate c. Oxalocetate d. Glutarate
|
||||
|
26) In TCA cycle substrate level phosphorylation occurs at____________? a. Succinate dehydrogenase b. Malonate reduction c. Thiokinase d. None of the above
|
||||
|
27) Which of the following is correctly matched ? a. Isocitrate to oxalo succinate -1 ATP is formed b. Succinyl CoA to succinate -1 ATP is formed c. Succinate to furmarate -1 ATP is formed d. Malate to oxaloacetate -1 ATP is formed
|
||||
|
28) The enzyme involved in the first committed step of glycolysis is____________? a. Phosphofructokinase b. Glucose-6-Phosphatase c. Hexokinase d. Enolase
|
||||
|
29) The end product of glycolysis under anaerobic conditions is_______________? a. Lactic acid b. Pyruvic acid c. Acetoacetic acid d. Oxaloacetic acid
|
||||
|
30) Which of the following is a non-reducing sugar____________? a. Glucose b. Maltose c. Lactose d. Sucrose
|
||||
